The Legend of Zelda: Twilight Princess is a 3D adventure starring Link, who is aided by a mystical shadow imp by the name of Midna in an attempt to save Hyrule from the mysterious Twilight that covers the land and to defeat Zant in order to restore peace to the people of the Twilight Realm.
Link is a young man residing in the village of Ordon. Here he leads a simple life, within a close knit community. One evening he is asked by one of the villagers to take a gift to Hyrule and the day that he is to leave, the village is attacked by a group of Bulbins that kidnap all the children of the village and then summon the Twilight to blanket the land. Link is consequently turned into a wolf after chasing the Bulbins into the Twilight itself and is taken to Hyrule Castle where he meets the imp girl, Midna.
This guide will give you the location of each boss, and how to beat them:
There are a few Differences between the Wii version of Twilight Princess and it's Gamecube counterpart
1. Some of the dialogue is slightly different
2. The map is completely mirrored
3. link is left-handed in the Gamecube version, right-handed on the Wii
 Items & Equipment
Here's a detailed list for all of the weapons and items used in Twilight Princess:
 Howling Stone & Wolf Locations